Homocystinuria: what about mild hyperhomocysteinaemia?

Homocystinuria: what about mild hyperhomocysteinaemia?

Hyperhomocysteinaemia is associated with an increased risk of atherosclerotic vascular disease and thromboembolism, in both men and women. A variety of conditions can lead to elevated homocysteine levels, but the relation between high levels and vascular disease is present regardless of the underlying cause. Pooled data from a large number of studies demonstrate that mild hyperhomocysteinaemia ...

Hyperhomocysteinaemia and multiple aneurysms.

Homozygous homocystinuria, the most common genetic disorder of transulphuration, is associated with elevated plasma concentrations of homocystine, homocysteine, multiple clinical abnormalities and life-threatening thromboembolism. Several instances of vascular aneurysms have also been documented. More recently, an association between premature occlusive vascular disease and the heterozygous sta...

06 Hyperhomocysteinaemia, hyperlipidaemia.pmd

1Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. 2Endocrine and Metabolism Research Centre, Nemazee Hospital, Shiraz, Islamic Republic of Iran. Received: 11/04/02; accepted: 02/02/03 ABSTRACT To assess the risk of venous thromboembolism (VTE) associated with hyperhomocysteinaemia (hyper-Hcy) and hyperlipidaemia, we performed a case–contr...

Hyperhomocysteinaemia in Behçet's Disease

Objectives. The aim of this study was to investigate if hyperhomocysteinaemia is a contributive risk factor for the pathogenesis and the activity of Behçet's disease (BD). Design and Methods. Fifty four patients fullfiling the criteria of the International Study Group for BD were enrolled. Fifty healthy volunteers matched for age and sex with the BD group were included as a negative control gro...

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